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Abruptio
Placenta
1
Definition
ā€¢ It is one form of Antepartum Hemorrhage
where the bleeding occurs due to
premature separation of a normally
situated placenta
2
Incidence
ā€¢ 0.5% - 1% of all deliveries
ā€¢ Decreasing trend
3
Risk factors
ā€¢ Increased age and parity
ā€¢ Preeclampsia
ā€¢ Chronic hypertension
ā€¢ Preterm ruptured membranes
ā€¢ Multi fetal gestation
ā€¢ Polyhydramnios
4
Risk factors
ā€¢ Cigarette smoking
ā€¢ Thrombophilias
ā€¢ Cocaine use
ā€¢ Prior abruption
ā€¢ Uterine leiomyoma
ā€¢ External Trauma
5
Retroplacental decidual hematoma
ā€¢ Separation, compression and destruction
of adjacent placenta
ā€¢ Varieties: Concealed, Revealed & mixed
ā€¢ Couvelaire uterus
6
PATHOLOGY
Clinical Features
Sign / symptom Frequency%
Vaginal bleeding 78
Uterine tenderness
back pain
66
Fetal distress 60
Preterm labor 22
Hypertonic contractions 17
Hyper tonus 17
Dead fetus 15
7
Diagnosisā€¦
Essentially a clinical diagnosis
ā€¢Painful bleeding
ā€¢Abdominal findings
ā€¢Cardiotocographic Monitoring
ā€¢ AFP
8
9
Cardiotocograph
Role of ultrasound ā€“ limited
ā€¢Negative findings do not exclude
the diagnosis
ā€¢U/S is mainly used to confirm fetal
viability, Presentation & position.
ā€¢To exclude Placenta praevia
10
Classification
Grade 0: Retrospective diagnosis.
Grade 1: External bleeding present, no fetal
or maternal complication
Grade 2: External bleeding +/-,
tense & tender uterus, Fetal
distress/death
Grade 3: External bleeding +/-
tense & tender uterus, fetal death with
maternal shock .
DIC, Renal failure
11
Consumptive Coagulopathy
ā€¢ Delee (1901) Temporary hemophilia
Parameters: Fibrinogen < 150 mg/dl,
ā€¢ elevated FDP, D-dimers, decrease in other
coagulation factors
Mechanism: DIC & retro placental clot
formation
ā€¢ Seen in 30% cases of abruption severe
enough to kill the fetus
12
Acute Renal failure
ā€¢ Pathology: Acute tubular necrosis (75%)
& acute cortical necrosis (25%)
ā€¢ Mechanism: Severe hypovolemia , DIC
along with Underlying preeclampsia
ā€¢ Prevention: Prompt & vigorous
replacement of blood and circulating blood
volume
13
Differential Diagnosis
1. Without pain: Placenta Previa
2. Without Bleeding: Acute degeneration
or torsion of a fibroid, hematoma of
rectus sheath, rupture of an
appendicular abscess.
3. With mild pain & bleeding: Labour with
heavy show
4. Rupture Uterus
14
Management
Initial assessment
ā€¢ Monitor vital signs: BP ā€“ poor guide to
the extent of bleeding.
ā€¢ Mark the fundal height & measure
abdominal girth
ā€¢ cardiotocographic monitoring of fetus
Investigations: HB, PCV, blood grouping
& typing, BT CT, Clot retraction & lyses,
DIC profile
ā€¢ Foley catheterization & hourly output
chart
ā€¢ watch for bleeding 15
Management
ā€œSwift & decisiveā€
Resuscitate the mother
ā€¢ Start an IV line, transfuse Ringer lactate, N
Saline
ā€¢ Two lines if bleeding is severe
ā€¢ Replace blood loss and maintain circulation
ā€¢ Maintain PCV at 30% & urine output >30
ml/hr.
ā€¢ CVP in difficult cases
ā€¢ Delivery
16
Management
Caesarian section
ā€¢ Live & mature fetus
ā€¢ Delivery not imminent
ā€¢ Fetal distress
ā€¢ No response to induction of labour
ā€¢ Bleeding
17
Management
Vaginal delivery
ā€¢ Preferred if fetus is dead.
ā€¢ In Selected cases with a live fetus
ā€¢ ARM with oxytocin
ā€¢ Watch for PPH
ā€¢ RH prophylaxis
18
Management
Expectant line of management
ā€¢ Doubtful diagnosis
ā€¢ Minor abruption
ā€¢ Preterm gestation
ā€¢ Intensive surveillance & Induction at
or before term
19
Perinatal mortality
ā€¢ Main danger is to the fetus. If the
abruption is severe enough to threaten the
mother, the fetus will usually be dead
25 fold increase in PMR
ā€¢ Still birth
ā€¢ Prematurity
ā€¢ Hypoxia
ā€¢ Cerebral palsy
20
Maternal deaths due to hemorrhage
Causes of hemorrhage Percentage
Abruption 19
Uterine rupture 16
Atonic PPH 15
Coagulopathies 14
Placenta praevia 7
Uterine bleeding 6
placenta accreta/percreta 6
Retained placenta 4
21
Maternal mortality
Case report: woman, who seemed well
enough to wait in an emergency dept for 2
hrs. When the doctor saw her at the end
of this time she was dead!!!
ā€œa fit woman may be able to compensate
for severe hemorrhage until collapse
occurs as a terminal eventā€
ā€¢ A reminder ā€“ need to maintain high
standards in obstetric care
22
23

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Abruptio placenta- Define, cause, sign and symptoms, Risk Factors, Incidence,pathology, Classification, Prevention and Treatment, management in PPT

  • 2. Definition ā€¢ It is one form of Antepartum Hemorrhage where the bleeding occurs due to premature separation of a normally situated placenta 2
  • 3. Incidence ā€¢ 0.5% - 1% of all deliveries ā€¢ Decreasing trend 3
  • 4. Risk factors ā€¢ Increased age and parity ā€¢ Preeclampsia ā€¢ Chronic hypertension ā€¢ Preterm ruptured membranes ā€¢ Multi fetal gestation ā€¢ Polyhydramnios 4
  • 5. Risk factors ā€¢ Cigarette smoking ā€¢ Thrombophilias ā€¢ Cocaine use ā€¢ Prior abruption ā€¢ Uterine leiomyoma ā€¢ External Trauma 5
  • 6. Retroplacental decidual hematoma ā€¢ Separation, compression and destruction of adjacent placenta ā€¢ Varieties: Concealed, Revealed & mixed ā€¢ Couvelaire uterus 6 PATHOLOGY
  • 7. Clinical Features Sign / symptom Frequency% Vaginal bleeding 78 Uterine tenderness back pain 66 Fetal distress 60 Preterm labor 22 Hypertonic contractions 17 Hyper tonus 17 Dead fetus 15 7
  • 8. Diagnosisā€¦ Essentially a clinical diagnosis ā€¢Painful bleeding ā€¢Abdominal findings ā€¢Cardiotocographic Monitoring ā€¢ AFP 8
  • 10. Role of ultrasound ā€“ limited ā€¢Negative findings do not exclude the diagnosis ā€¢U/S is mainly used to confirm fetal viability, Presentation & position. ā€¢To exclude Placenta praevia 10
  • 11. Classification Grade 0: Retrospective diagnosis. Grade 1: External bleeding present, no fetal or maternal complication Grade 2: External bleeding +/-, tense & tender uterus, Fetal distress/death Grade 3: External bleeding +/- tense & tender uterus, fetal death with maternal shock . DIC, Renal failure 11
  • 12. Consumptive Coagulopathy ā€¢ Delee (1901) Temporary hemophilia Parameters: Fibrinogen < 150 mg/dl, ā€¢ elevated FDP, D-dimers, decrease in other coagulation factors Mechanism: DIC & retro placental clot formation ā€¢ Seen in 30% cases of abruption severe enough to kill the fetus 12
  • 13. Acute Renal failure ā€¢ Pathology: Acute tubular necrosis (75%) & acute cortical necrosis (25%) ā€¢ Mechanism: Severe hypovolemia , DIC along with Underlying preeclampsia ā€¢ Prevention: Prompt & vigorous replacement of blood and circulating blood volume 13
  • 14. Differential Diagnosis 1. Without pain: Placenta Previa 2. Without Bleeding: Acute degeneration or torsion of a fibroid, hematoma of rectus sheath, rupture of an appendicular abscess. 3. With mild pain & bleeding: Labour with heavy show 4. Rupture Uterus 14
  • 15. Management Initial assessment ā€¢ Monitor vital signs: BP ā€“ poor guide to the extent of bleeding. ā€¢ Mark the fundal height & measure abdominal girth ā€¢ cardiotocographic monitoring of fetus Investigations: HB, PCV, blood grouping & typing, BT CT, Clot retraction & lyses, DIC profile ā€¢ Foley catheterization & hourly output chart ā€¢ watch for bleeding 15
  • 16. Management ā€œSwift & decisiveā€ Resuscitate the mother ā€¢ Start an IV line, transfuse Ringer lactate, N Saline ā€¢ Two lines if bleeding is severe ā€¢ Replace blood loss and maintain circulation ā€¢ Maintain PCV at 30% & urine output >30 ml/hr. ā€¢ CVP in difficult cases ā€¢ Delivery 16
  • 17. Management Caesarian section ā€¢ Live & mature fetus ā€¢ Delivery not imminent ā€¢ Fetal distress ā€¢ No response to induction of labour ā€¢ Bleeding 17
  • 18. Management Vaginal delivery ā€¢ Preferred if fetus is dead. ā€¢ In Selected cases with a live fetus ā€¢ ARM with oxytocin ā€¢ Watch for PPH ā€¢ RH prophylaxis 18
  • 19. Management Expectant line of management ā€¢ Doubtful diagnosis ā€¢ Minor abruption ā€¢ Preterm gestation ā€¢ Intensive surveillance & Induction at or before term 19
  • 20. Perinatal mortality ā€¢ Main danger is to the fetus. If the abruption is severe enough to threaten the mother, the fetus will usually be dead 25 fold increase in PMR ā€¢ Still birth ā€¢ Prematurity ā€¢ Hypoxia ā€¢ Cerebral palsy 20
  • 21. Maternal deaths due to hemorrhage Causes of hemorrhage Percentage Abruption 19 Uterine rupture 16 Atonic PPH 15 Coagulopathies 14 Placenta praevia 7 Uterine bleeding 6 placenta accreta/percreta 6 Retained placenta 4 21
  • 22. Maternal mortality Case report: woman, who seemed well enough to wait in an emergency dept for 2 hrs. When the doctor saw her at the end of this time she was dead!!! ā€œa fit woman may be able to compensate for severe hemorrhage until collapse occurs as a terminal eventā€ ā€¢ A reminder ā€“ need to maintain high standards in obstetric care 22
  • 23. 23