Rubella, also known as “German Measles‘’, is caused by the rubella virus and it can be transmitted to a pregnant woman via respiratory droplets. Most children from 12 to 15 months of age get the MMR vaccine against measles, mumps, and rubella.
Rubella virus can be transmitted to a pregnant woman via respiratory droplets. Another route for Rubella to spread is from a pregnant woman to her unborn child, through the placenta. This causes congenital rubella syndrome in the fetus.
Neonates born with congenital rubella syndrome usually have a tetrad of symptoms: hearing loss or deafness, eye abnormalities, dermal extramedullary hematopoiesis and congenital heart disease.
Congenital Rubella Syndrome (CRS), which can occur when a woman is infected with rubella during pregnancy, can lead to a variety of possible birth defects. According to CDC, CRS cases can be diagnosed in newborns and infants through rubella IgM detection. Suspected cases should be tested as close to birth as possible and again at 1 month of age if the initial IgM test result is negative[1].
With CE IVDR certificate, Mindray has developed reliable ToRCH serological tests with high sensitivity and specificity for our customers.
References
1. https://www.cdc.gov/rubella/lab/serology.html
2. Emeritus Prof JE Banatvala FRCPath , DWG Brown FRCPath. "Rubella." The Lancet, Volume 363, Issue 9415, 3 April 2004, Pages 1127-1137
