Gaucher Disease Market Challenges, Analysis and Forecast to 2032
The market for Gaucher disease was estimated at USD 980.0 million in 2021, and it is anticipated to grow at a CAGR of 8.5% to reach around USD 1,800.0 million in 2029.
Market Analysis and Size
A genetic metabolic disorder called Gaucher disease prevents the decomposition of the lipid glucocerebroside. In the human organism, an enzyme called glucocerebrosidase degrades and reprocesses glucocerebroside. Mutations in the GBA gene, which lead to very low amounts of the glucocerebrosidase enzyme and slow glucocerebroside breakdown, are the cause of Gaucher disease. There are three different kinds of Gaucher disease: type 1, type 2, or type 3. There are three types of Gaucher disease: types 1, 2, and 3. The prevalence of type 1 is highest, while type 2 and type 3 are less prevalent.
Market Definition
A buildup of fatty substances in your tissues, particularly your spleen and liver, is what causes Gaucher disease. This causes these organs to grow, which may affect how well they work. Although there is no known cure for Gaucher disease, there are a number of treatments that can help control symptoms, prevent permanent harm, and improve quality of life. In enzyme replacement treatment, artificial enzymes are used to replace the damaged enzyme. The three ERT medications presently approved by the FDA are iglucerase, velaglucerase alfa, and taliglucerase. (Elelyso). Analgesics for bone pain, joint replacement surgery for chronic pain relief and function restoration, transfusions of blood products for extreme anaemia and bleeding, anti-bone resorption medications, calcium, and vitamin D for osteoporosis, and analgesics for bone pain.
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Some of the key players operating in the global Gaucher disease market include:
• Genzyme Corporation (Sanofi)
• Pfizer, Inc.
• Shire Human Genetics Therapies, Inc.
• Actelion Pharmaceuticals Ltd. (Johnson & Johnson)
• AVROBIO, Inc.
• Bristol-Myers Squibb Company
• PerkinElmer Inc.
• Amicus Therapeutics, Inc.
• Moderna, Inc.
• Greenovation Biotech GmbH
• Biomarin
• Takeda Pharmaceutical Company Limited
• AstraZeneca PLC
• Eli Lilly and Company
• Other players
Segments
By Disease Type
• Type 1 Gaucher disease
• Type 2 Gaucher disease
• Type 3 Gaucher disease
By Therapy Type
• Enzyme Replacement Therapy (ERT)
• Substrate Reduction Therapy (SRT)
By End Users
• Hospitals
• Specialty Clinics
• Homecare
• Others
By Distribution Channel
• Hospitals
• Retail Pharmacies
• Online Pharmacies
By Geography
• North America
o U.S.
o Canada
o Mexico
• Europe
o U.K.
o Germany
o France
o Italy
o Spain
o Russia
• Asia-Pacific
o Japan
o China
o India
o Australia
o South Korea
o ASEAN
• Latin America
o Brazil
o Argentina
o Colombia
• MEA
o South Africa
o Saudi Arabia
o UAE
o Egypt
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