AJOG Expert Review in Labor: Placental abruption at near-term and term gestations: pathophysiology, epidemiology, diagnosis, and management - Pathophysiology of placental abruption Placental abruption is the end result of an acute process (“acute pathway”), the culmination of long-standing chronic processes (“chronic pathway”), or both. The acute pathway is driven by mechanical and shearing forces applied to the abdomen, causing premature placental separation. The chronic pathway includes thrombosis, infection, and decidual and uteroplacental vasculopathy and other inflammatory processes. http://ow.ly/hMJT50OhyBu