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2022, World Journal of Surgical Oncology
Background Primary soft tissue sarcomas contribute to only 2% of all malignancies arising from the male genitourinary tract. Leiomyosarcoma (LMS) is a malignant soft tissue neoplasm which originates from the mesenchyme and has a characteristic smooth muscle differentiation. Usually, it presents as a painless, firm, slow-growing unilateral scrotal mass. Investigations include imaging, tumor markers, and histopathology. Case presentation A 65-year-old gentleman known diabetic and beta-thalassemic trait was referred to the Urology OPD at Letterkenny University Hospital. His presenting complaint was a left groin lump that appeared 1 year ago and was growing larger in size gradually. According to the patient, his lump was slightly painful (localized) initially that later became painless. He did not report any testicular trauma/infection or UTI. There was no significant history of malignancies running through his family. Clinical examination revealed a soft and lax abdomen, normal testes....
2022 •
Background:Primary soft tissue sarcomas contribute to only 2% of all malignancies arising from the male genitourinary tract. Leiomyosarcoma (LMS) is a malignant soft tissue neoplasm which originates from the mesenchyme and has a characteristic smooth muscle differentiation. Usually, it presents as a painless, firm, slow growing unilateral scrotal mass. Investigations include imaging, tumour markers and histopathology. Case Presentation:A 65 year old gentleman known Diabetic and Beta-thalassemic trait was referred to Urology OPD at Letterkenny University Hospital. His presenting complaint was left groin lump which appeared one year ago and was growing larger in size gradually. According to the patient his lump was slightly painful(localized) initially, that later became painless. He did not report any testicular trauma/infection or UTI. There was no significant history of malignancies running through his family. Clinical examination revealed soft and lax abdomen, normal testes. There...
Pathology International
LEIOMYOSARCOMA OF THE SPERMATIC CORD: A Case Report and a Brief Review of Literature2008 •
Diagnostic Pathology
Adult primary paratesticular mesenchymal tumors with emphasis on a case presentation and discussion of spermatic cord leiomyosarcoma2014 •
Spermatic cord Leiomyosarcoma is an extremely rare intrascrotal tumour. Owing to its rarity, no definitive management guidelines have been formulated as yet. The majority of published literature comprises of case reports or case series and show varying outcomes depending upon multiple patient-and disease-related factors. Almost all cases are older adults with majority in the sixth or seventh decades of life. It is commonly labelled as an indolent curable tumour if treated early by radical orchiectomy. The role of lymphadenectomy, adjuvant radiotherapy or chemotherapy is unclear. This case report concerns a young 38-year-old man who suffered from a painless firm left hemiscrotal mass for the past two years. Ultrasonography showed an intrascrotal paratesticular mass. Metastatic workup was negative. Left radical orchiectomy was performed and histopathology of the surgical specimen revealed leiomyosarcoma of the spermatic cord. The patient is on post-surgery follow-up and disease-free for six months. A literature review is also presented.
Minerva chirurgica
[Leiomyosarcoma of the spermatic cord]The case of leiomyosarcoma of the spermatic cord in a 54 year old man is reported. The patient was treated by surgical orchiepididymectomy and funnilectomy. After a review of the literature, the clinical and anatomopathological feature of this rare tumour and the surgical approach to it are discussed. The patient has had no recurrences and is still alive 16 months after surgery.
World Journal of …
Imaging features of a huge spermatic cord leiomyosarcoma: Review of the literature2011 •
Author contributions: All authors contributed in the therapeutic approach of the patient (U/S: Antypa E and Kyratzi I, CT: Exarhos D and Kyratzi I, Surgery: Lolis E, Pathologic exams: Lianou MA) and they wrote the part of the paper corresponding to their exam; Kyratzi I made literature ...
Case Reports in Urology
Rare Case of a Well-Differentiated Paratesticular Sarcoma of the Spermatic Cord in a 60-Year-Old Patient2017 •
Introduction. Liposarcomas are tumors that occur mostly in the retroperitoneum. Of all liposarcomas only 3 to 7% are found in the paratesticular region. The spermatic cord is the main site of origin in these cases. The patients ages range from 50 to 60 years. This malignant disease can result in a loss of fertility aside from life-threatening sequelae.Case. We present a case of a liposarcoma of the paratesticular region. A 60-year-old man was referred with a painless mass in the scrotum and the right inguinal region. The patient underwent surgery and the mass was removed along with the right testis, the spermatic cord, and the soft tissues to the internal inguinal ring. Histopathological examination found a well-differentiated liposarcoma of80⁎80 mm. The surgical margins were negative. The adjuvant treatment consisted in radiation therapy of the right inguinoscrotal area to the dose of 54 Gray, 2 Gy per session, 5 times a week.Conclusion. Paratesticular liposarcomas are rare tumors....
Journal of Cancer Science and Clinical Therapeutics
A Slow Growing Paratesticular Leiomyosarcoma: An Unusual Case Report2020 •
World journal of surgical oncology
Management of leiomyosarcomas of the spermatic cord: the role of reconstructive surgery2005 •
BACKGROUND: Leiomyosarcomas (LMS) of the spermatic cord are extremely rare. Radical inguinal orchiectomy and high ligation of the cord is the standard primary surgical procedure. The extent of surrounding soft tissue excision required and the precise role of adjuvant radiotherapy, however, remains unclear. In addition, recurrence is a commonly encountered problem which might necessitate further radical excision of adjacent soft tissues. METHODS: This article reviews the pathophysiology of spermatic cord leiomyosarcomas (LMS), and discusses the various reconstructive surgical options available to repair the inguinal region and the lower anterior abdominal wall after excision of the tumour and the adjacent soft tissues. RESULTS: There is paucity of literature on LMS of spermatic cord. The majority of paratesticular neoplasms are of mesenchymal origin and up to 30% of these are malignant. In adults, approximately 10% of spermatic cord sarcomas are LMS. Approximately 50% of these tumour...
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