Abstract
The bicornuate uterus is a type of congenital uterine anomaly that occurs due to a lateral fusion defect of the müllerian ducts during embryologic development. This results in several anatomic variations including partial or complete divisions between the endometrial cavities, single or duplicated cervices, and associated vaginal anomalies. Women with a bicornuate uterus may be identified at the time of pregnancy, during evaluation of poor obstetrical outcomes or during evaluation of an obstructing or nonobstructing vaginal anomaly, but many women are asymptomatic and remain undiagnosed. Evaluating women with a possible uterine anomaly requires a detailed history and physical examination. In addition, appropriate imaging is necessary in order to differentiate the bicornuate uterus from other uterine anomalies. Furthermore, women with uterine anomalies commonly warrant imaging of the urinary tract to assess for associated anomalies. For women with a bicornuate uterus, conception does not appear to be affected; however, there is an increased risk of obstetrical complications such as recurrent pregnancy loss, preterm labor, intrauterine growth restriction, placental abruption, and cervical incompetence. Surgical intervention with the Strassman metroplasty or cervical cerclage should be considered in select women with a history of recurrent poor obstetrical outcomes.
References
Speroff L, Fritz M. Clinical gynecologic endocrinology and infertility. 8th ed. Philadelphia: Lippincott Williams & Wilkins; 2010. p. 1191–220.
Saravelos SH, Cocksedge KA, Li TC. Diagnosis of congenital uterine anomalies in women with reproductive failure: a critical appraisal. Hum Reprod Update. 2008;14:415–29.
Troiano RN, McCarthy SM. Mullerian duct anomalies: imaging and clinical issues. Radiology. 2004;233(1):19.
Grimbizis GF, Camus M, Tarlatzis BC, Bontis JN, Delvoy P. Clinical implications of uterine malformations and hysteroscopic treatment results. Hum Reprod Update. 2001;7:161–74.
Rackow BW. Congenital uterine anomalies. In: Stadtmauer L, Tur-Kaspa I, editors. Ultrasound imaging in reproductive medicine: advances in infertility work-up, treatment and art. New York: Springer; 2014. p. 101–16.
Wu MH, Hsu CC, Huang KE. Detection of congenital müllerian duct anomalies using three-dimensional ultrasound. J Clin Ultrasound. 1997;25:487–92.
Reichman DE, Laufer MR. Congenital uterine anomalies affecting reproduction. Best Pract Res Clin Obstet Gynaecol. 2010;24:193–208.
Toaff ME, Lev-Toaff AS, Toaff R. Communicating uteri: review and classification with introduction of two previously unreported types. Fertil Steril. 1984;41:661–79.
Oppelt P, von Have M, Paulsen M, Strissel PL, Strick R, Brucker S, et al. Female genital malformations and their associated abnormalities. Fertil Steril. 2007;87:335–42.
Rackow BW, Arici A. Reproductive performance of women with müllerian anomalies. Curr Opin Obstet Gynecol. 2007;19(3):229–37.
Goldberg J, Falcone T. Mullerian anomalies: reproduction, diagnosis and treatment. In: Gidwani G, Falcone T, editors. Congenital malformations of the female genital tract: diagnosis and management. Philadelphia: Lippincott Williams and Wilkins; 1999. p. 177–204.
Szkodziak P, Woźniak S, Czuczwar P, Paszkowski T, Milart P, Wozniakowska E, Szlichtyng W. Usefulness of three dimensional transvaginal ultrasonography and hysterosalpingography in diagnosing uterine anomalies. Ginekol Pol. 2014;85(5):354–9.
Salim R, Jurkovic D. Assessing congenital uterine anomalies: the role of three-dimensional ultrasonography. Best Pract Res Clin Obstet Gynecol. 2004;18:29–36.
Moini A, Mohammadi S, Hosseini R, Eslami B, Ahmadi F. Accuracy of 3-dimensional sonography for diagnosis and classification of congenital uterine anomalies. J Ultrasound Med. 2013;32(6):923–7.
Ghi T, Casadio P, Kuleva M, Perrone AM, Savelli L, Giunchi S, et al. Accuracy of three-dimensional ultrasound in diagnosis and classification of congenital uterine anomalies. Fertil Steril. 2009;92:808–13.
Ludwin A, Pityński K, Ludwin I, Banas T, Knafel A. Two- and three-dimensional ultrasonography and sonohysterography versus hysteroscopy with laparoscopy in the differential diagnosis of septate, bicornuate, and arcuate uteri. J Minim Invasive Gynecol. 2013;20(1):90–9.
Faivre E, Fernandez H, Deffieux X, Gervaise A, Frydman R, Levaillant JM. Accuracy of three-dimensional ultrasonography in differential diagnosis of septate and bicornuate uterus compared with office hysteroscopy and pelvic magnetic resonance imaging. J Minim Invasive Gynecol. 2012;19(1):101–6.
Yoo RE, Cho JY, Kim SY, Kim SH. A systematic approach to the magnetic resonance imaging-based differential diagnosis of congenital Müllerian duct anomalies and their mimics. Abdom Imaging. 2015;40(1):192–206.
Bermejo C, Ten Martinez P, Cantarero R, Diaz D, Perez Pedregosa J, Barron E, et al. Three-dimensional ultrasound in the diagnosis of Müllerian duct anomalies and concordance with magnetic resonance imaging. Ultrasound Obstet Gynecol. 2010;35:593–601.
Lin PC, Bhatnagar KP, Nettleton GS, Nakajima ST. Female genital anomalies affecting reproduction. Fertil Steril. 2002;78:899–915.
Letterie G. Surgery, assisted reproductive technology and infertility: diagnosis and management of problems in gynecologic reproductive medicine. 2nd ed. Boca Raton: CRC; 2007. p. 149–80.
Rock JA, Breech LL. Surgery for anomalies of the mullerian ducts. In: Rock JA, Jones III HW, editors. Te Linde’s operative gynaecology. 10th ed. Philadelphia: Lippincott-Williams & Wilkins; 2008. p. 572–5.
Lolis DE, Paschopoulos M, Makrydimas G, Zikopoulos K, Sotiriadis A, Paraskevaidis E. Reproductive outcome after Strassman metroplasty in women with a bicornuate uterus. J Reprod Med. 2005;50(5):297–301.
Rechberger T, Monist M, Bartuzi A. Clinical effectiveness of Strassman operation in the treatment of bicornuate uterus. Ginekol Pol. 2009;80(2):88–92.
Propst AM, Hill III JA. Anatomic factors associated with recurrent pregnancy loss. Semin Reprod Med. 2000;18:341–50.
Alborzi S, Asefjah H, Amini M, Vafaei H, Madadi G, Chubak N, Tavana Z. Laparoscopic metroplasty in bicornuate and didelphic uteri: feasibility and outcome. Arch Gynecol Obstet. 2015;291(5):1167–71.
Chan YY, Jayaprakasan K, Zamora J, Thornton JG, Raine-Fenning N, Coomarasamy A. The prevalence of congenital uterine anomalies in unselected and high-risk populations: a systematic review. Hum Reprod Update. 2011;17:761–71.
Hua M, Odibo A, Longman R, Macones G, Roehl K, Cahill A. Congential uterine anomalies and adverse pregnancy outcomes. Am J Obstet Gynecol. 2011;6:558.
Acien P. Reproductive performance of women with uterine malformations. Hum Reprod. 1993;8:122–6.
Heinonen PK, Saarikoski S, Pystynen P. Reproductive performance of women with uterine anomalies: an evaluation of 182 cases. Acta Obstet Gynecol Scand. 1982;61:157.
Raga F, Bauset C, Remohi J, Bonilla-Musoles F, Simon C, Pellicer A. Reproductive impact of congenital müllerian anomalies. Hum Reprod. 1997;12:2277–81.
Yassaee F, Mostafaee L. The role of cervical cerclage in pregnancy outcome in women with uterine anomaly. J Reprod Infertil. 2011;12(4):277–9.
Author information
Authors and Affiliations
Corresponding author
Editor information
Editors and Affiliations
Rights and permissions
Open Access This chapter is distributed under the terms of the Creative Commons Attribution Noncommercial License, which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.
Copyright information
© 2016 Springer International Publishing Switzerland
About this chapter
Cite this chapter
Zakarin Safier, L., Rackow, B.W. (2016). Bicornuate Uterus. In: Pfeifer, S. (eds) Congenital Müllerian Anomalies. Springer, Cham. https://doi.org/10.1007/978-3-319-27231-3_8
Download citation
DOI: https://doi.org/10.1007/978-3-319-27231-3_8
Published:
Publisher Name: Springer, Cham
Print ISBN: 978-3-319-27229-0
Online ISBN: 978-3-319-27231-3
eBook Packages: MedicineMedicine (R0)