Abstract
Purpose
Mucinous ovarian tumors, i.e., mucinous cystadenomas, have been found to coexist with Brenner tumors and therefore studied more commonly. We report here this case report with emphasis on its clinical features, diagnostic, morphological and histological features.
Method
A 70-year-old patient who attended outpatient department at GCRI, Ahmedabad, underwent exploratory laparotomy after proper surgical evaluation for bilateral adnexal masses on clinical examination and imaging.
Result
In this case report, Brenner tumor was found to coexist with borderline mucinous cystadenocarcinoma in left and right ovary, respectively, on frozen section. The final histopathology showed borderline mucinous cystadenocarcinoma in right ovary and benign Brenner tumor in left ovary.
Conclusion
The rate of Brenner tumor coexisting with mucinous cystadenoma has been reported as 1.3%, and the rate of mucinous adenocarcinoma accompanying Brenner tumor has been reported as 9%.
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References
Ehdaivand S. WHO classification of ovarian neoplasms. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/ovarytumorwhoclassif.html.
Oh SN, Rha SE, Jung SE, Lee YJ, Choi BG, Byun JY, Ku YM, Jung CK. Transitional cell tumor of the ovary: computed tomographic and magnetic resonance imaging features with pathological correlation. J Comput Assist Tomogr. 2009;33:106–12.
Sridevi S, Rao VM, Kumar SS, Bhagyalakshmi A. Mucinous cystadenoma with brenner tumor: a case report. J Evid Based Med Healthcare. 2015;2(4):455–8.
Fox H, Wells M. Surface epithelial stromal tumor of the ovary. In: Fox H, Wells M, editors. Haines & Taylor obstetrical and gynaecological pathology, vol. 1. Madrid: Churchill Livingstone; 2003. p. 42.
Seidman JD, Khedmati F. Exploring the histogenesis of ovarian mucinous and transitional cell (Brenner) neoplasms and their relationship with Walthard cell nests; a study of 120 tumors. Arch Pathol Lab Med. 2008;132:1753–60.
Wasim S, Ahmad S. Right serous cystadenoma with left brenner tumour in a post-menopausal female: a rare case of bilateral ovarian tumor. Res Rev J Med Health Sci RRJMHS. 2014;3(4):59–62.
Pejovic T, Bürki N, Odunsi K, Fiedler P, Achong N, Schwartz PE, Ward DC. Well-differentiated mucinous carcinoma of the ovary and a coexisting brenner tumor both exhibit amplification of 12q14 − 21 by comparative genomic hybridization. Gynecol Oncol. 1999;74(1):134–7.
Hart WR. Mucinous tumors of the ovary: a review. Int J Gynecol Pathol. 2005;24:4–25.
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Goel, P., Dave, P.S., Patel, B. et al. Benign Brenner Tumor and Borderline Mucinous Cystadenocarcinoma Coexisting Together: A Rare Case Report. Indian J Gynecol Oncolog 17, 19 (2019). https://doi.org/10.1007/s40944-019-0264-7
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DOI: https://doi.org/10.1007/s40944-019-0264-7