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Forty years of development of salpingitis animal modeling

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Abstract

This review summarizes and examines research in the area of salpingitis animal modeling in the last 40 years, focusing primarily on Chlamydia trachomatis animal models, which are the most numerous in the literature. Early animal models are examined, followed by a discussion of study parameters and their impact on modeling success, subsequent considerations of fertility measures in modeling, explorations of treatment options, and finally exploring recent directions with a brief discussion of models using other bacterial pathogens.

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Funding

Supported by Sichuan Science and Technology Program (Grant No. 2022YFS0415). National Natural Science Foundation of China (Grant No. 82205175).

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Author notes

  1. Yefang Huang and Boyu Zhu are joint first authors of this manuscript.

Authors and Affiliations

  1. Department of Obstetrics and Gynecology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, Sichuan, China

    Yefang Huang, Boyu Zhu, Xiaoli Ji, Yi Wen, Yan Wang & Xiang Hu

  2. Department of Geriatrics, Hospital of Chengdu University of Traditional Chinese Medicine, No. 39 Shi-Er-Qiao Road, Chengdu, Sichuan Province, China, 610072

    Ye Yuan

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  1. Yefang Huang
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  5. Yan Wang
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Contributions

YH: date collection, manuscript writing, project development. BZ: date collection, manuscript writing. XJ: data analysis. YW: data analysis. YW: project development, date collection. XH: project development, date Collection. YY: project development.

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Correspondence to Ye Yuan.

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Huang, Y., Zhu, B., Ji, X. et al. Forty years of development of salpingitis animal modeling. Arch Gynecol Obstet 308, 1093–1112 (2023). https://doi.org/10.1007/s00404-023-06966-1

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  • DOI: https://doi.org/10.1007/s00404-023-06966-1

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