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Cytomegalovirus Infection, Congenital

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Encyclopedia of Molecular Mechanisms of Disease

Synonyms

CMV infection

Definition and Characteristics

About 90% of infants with congenital cytomegalovirus (CMV) infection are asymptomatic at birth. Jaundice (62%), petechiae (58%), and hepatosplenomegaly (50%) are the most frequently noted classical triad in symptomatic infants (Fig. 1) [1].

Cytomegalovirus Infection, Congenital. Figure 1
figure 1_3373

A newborn infant with symptomatic congenital CMV infection presenting with petechiae, jaundice, and hepatosplenomegaly.

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References

  1. Leung AK, Sauve RS, Davies HD (2003) J Natl Med Assoc 95:213–217

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  2. Nelson CT, Demmler GJ (1997) Clin Perinatol 24:151–160

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  3. Boppana SB, Fowler KB, Britt WJ et al. (1999) Pediatrics 104:55–60

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  4. Smets K, de Coen K, Dhooge I et al. (2006) Eur J Pediatr 165:885–890

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Leung, A.K.C., Sauve, R.S. (2009). Cytomegalovirus Infection, Congenital. In: Lang, F. (eds) Encyclopedia of Molecular Mechanisms of Disease. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-540-29676-8_3373

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